This is a great Expression web 2 part tutorial on creating an ASP.NET contact form that sends e-mail.
In the first part of this tutorial, you'll learn how to create the user-interface portion of the form and add ASP.NET validation so that the fields are required and valid.
The second part of the tutorial covers the server-side C# code that sends the e-mail. Downloadable examples in both VB and C# also area available.
See the tutorials here.